Thyroid Function Tests
TSH, free T4/T3, thyroid antibodies, and clinical interpretation
Lakshmi Nair, 62F
TFT-2026-0441 · SLE — monitoring for thyroid disease (autoimmune) · Dr. R. Kumar (Rheumatology)
Overt Hyperthyroid
| Analyte | Value | Unit | Reference | Flag |
|---|---|---|---|---|
| TSH (Thyroid Stimulating Hormone) | 0.02 ↓ | mIU/L | 0.35–5.50 | Suppressed |
| Free T4 (FT4) | 28.4 ↑ | pmol/L | 9.0–19.1 | High |
| Free T3 (FT3) | 9.2 ↑ | pmol/L | 2.6–5.7 | High |
| Anti-TPO Antibodies | > 600 ↑ | IU/mL | < 34 | High |
| Anti-Thyroglobulin Antibodies | 420 ↑ | IU/mL | < 115 | High |
Overt hyperthyroidism: suppressed TSH with elevated FT4 and FT3. Markedly elevated Anti-TPO and Anti-Tg antibodies — consistent with Graves' disease or autoimmune thyroiditis (Hashimoto's thyrotoxic phase). Urgent endocrinology referral. Consider antithyroid drugs (carbimazole). ECG for atrial fibrillation.
Asha Patel, 24F
TFT-2026-0440 · Pre-conception counselling — known hypothyroidism on levothyroxine · Dr. S. Mehta (Gynaecology)
Sub-optimal
| Analyte | Value | Unit | Reference | Flag |
|---|---|---|---|---|
| TSH | 2.8 ↑ | mIU/L | 0.35–2.5 (pre-conception target) | High |
| Free T4 (FT4) | 14.2 | pmol/L | 9.0–19.1 | Normal |
TSH 2.8 — above target of < 2.5 for pre-conception. Increase levothyroxine dose from 75 mcg to 100 mcg. Recheck in 4-6 weeks. Target TSH < 2.5 before conception and maintain < 4.0 in pregnancy.