Haematology Oncology
Haematological malignancy management — leukaemia, lymphoma, myeloma, and bone marrow transplant
Neutrophils 0.4 × 10⁹/L — severe neutropenia (post-induction AML). Protective isolation mandatory. Empirical antibiotics within 1h of fever.
Patient: Arun Singh, 38M
UHID: UH-2026-0820
Diagnosis: AML — NPM1 mutated, FLT3-ITD negative
ELN Risk: Favourable
Treatment: Induction: 7+3 (Cytarabine + Daunorubicin) — Day 14
Last BME: Day 14 — awaiting result
Day 14 Bloods & Toxicity
| Parameter | Value | Flag | Action |
|---|---|---|---|
| WBC | 0.6 × 10⁹/L | Critical | Protective isolation, G-CSF deferred (AML — avoid) |
| Neutrophils | 0.4 × 10⁹/L | Severe | Empirical antibiotics if fever > 38°C |
| Haemoglobin | 72 g/L | Low | Transfuse: 2 units pRBC (trigger < 80 g/L) |
| Platelets | 12 × 10⁹/L | Critical | Prophylactic platelet transfusion (trigger < 20) |
| Creatinine | 88 µmol/L | Normal | Continue monitoring |
| Bilirubin | 24 µmol/L | Normal | Monitor for hepatic toxicity |